Use the Following Information to Answer Questions

question 4

Multiple Choice

Use the following information to answer questions
About 1 in every 100 Caucasians suffers from celiac disease. These individuals have severe allergic responses and digestive problems when they eat certain grains. Their illness is caused specifically by gluten, a protein found in wheat, barley, and rye. Treatments for this disease often rely on dietary supplements that contain protein-degrading enzymes that can break down the gluten during normal digestion, making it harmless.

One such enzyme is called AN-PEP (an abbreviation for prolyl endoprotease) , and it is isolated from the fungus Aspergillus niger. Various research groups are investigating ways to use this enzyme to treat humans. One group is researching the possibility of adding the gene for AN-PEP to wheat so that gluten protein will be detoxified at the very source.

-The wheat cells manipulated by the research group would probably contain

• A) a fungal AN-PEP gene fused to a wheat regulatory sequence.
• B) a wheat AN-PEP gene fused to a fungal regulatory sequence.
• C) a wheat AN-PEP gene fused to a wheat regulatory sequence.
• D) a fungal AN-PEP gene fused to a fungal regulatory sequence.
• E) a human AN-PEP gene fused to a wheat regulatory sequence.

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