For Those Women with a Mutation in Their BRCA Genes,the

question 132

Multiple Choice

For those women with a mutation in their BRCA genes,the risk of developing breast cancer by age 50 is as high as _________,while in the general population the risk is _________.

• A) 10%;<5%
• B) 20%;<5%
• C) 20%;10%
• D) 50%;<5%
• E) 50%;20%

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Definitions:

Mosaic Development

A developmental pattern marked by the autonomous development of parts of an organism, such that the fate of each cell is determined early and independently of other cells.

Founder Cells

Cells that originate a population or tissue and possess the genetic information and proliferative ability to sustain the population.

Homeodomain

A functional region of certain transcription factors; consists of approximately 60 amino acids specified by a homeobox DNA sequence and includes a recognition alpha helix, which binds to specific DNA sequences and affects their transcription.

Amino Acids

Organic compounds that combine to form proteins, essential for the structure, function, and regulation of the body's cells, tissues, and organs.