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In signature-tagged mutagenesis, the tag is:
Mental Disorders
Medical conditions that involve changes in cognition, emotions, or behaviors leading to distress or difficulty in functioning.
Treat
To act or behave towards someone or something in a specified manner, often with kindness or to provide something pleasurable.
Severe Depression
A major depressive disorder characterized by a deep and persistent feeling of sadness or despair and/or a loss of interest in activities, accompanied by several physical and emotional problems.
Euphoric
A feeling of intense excitement and happiness.
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