A Paracentric Inversion Heterozygote Contains a Normal Chromosome with the Long-Arm

question 23

Essay

A paracentric inversion heterozygote contains a normal chromosome with the long-arm gene order GENE and an inverted chromosome with the long-arm gene order GNEE.They form an inversion loop to pair during prophase I of meiosis.If a single crossover occurs between the G and the E segments of the loop,what will be the gene orders in the resulting recombinant dicentric chromosome and acentric fragment? Assume crossing over occurs at the four-strand stage involving two nonsister chromatids.

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