Why Does DNA Denature When the PH Is Raised Above

question 25

Multiple Choice

Why does DNA denature when the pH is raised above 9?

• A) Protons dissociate from guanine bases disrupting the hydrogen bonding to the other strand.
• B) Protons bind to guanine residues giving them additional positive charges which disrupt the hydrogen bonding to the other strand.
• C) Protons bind to functional groups that serve as hydrogen-bond acceptors, thus disrupting the hydrogen bonding to the other strand.
• D) Protons dissociate from the phosphate groups in the backbone, which disrupts the hydrogen-bonding pattern between strands.
• E) None of the answers is correct.

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