Binding of a Water Molecule to the Zinc Ion Induces

question 24

Multiple Choice

Binding of a water molecule to the zinc ion induces

• A) a hydronium ion to form.
• B) a large conformation change in the binding site.
• C) ionization of a His residue, which functions as a strong nucleophile.
• D) a lowered pK_a for water, which leads to formation of a zinc bound hydroxide ion.
• E) an altered K_M value.

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