Positional Cloning

question 13

Multiple Choice

Positional cloning

• A) seeks regions of the genome shared by the members of large families who have the same Mendelian disorder.
• B) scans and then sequences the human genome chromosome by chromosome, in size order.
• C) determines the sequence of protein-encoding genes on a chromosome.
• D) identifies expressed sequence tags in genes of interest.
• E) cuts several copies of the human genome into pieces and aligns them to derive the overall sequence.

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Definitions:

Cell Membrane

A biological membrane that separates the interior of all cells from the outside environment, regulating the passage of substances.

Transmembrane Protein

An integral membrane protein that spans the lipid bilayer.

Glycoprotein

Glycoproteins are proteins that have sugar molecules attached to them, playing crucial roles in cell-cell recognition and immune responses.

Covalently Linked

Atoms connected by covalent bonds, where they share one or more pairs of electrons to achieve stability.