Matthew Has the Inherited Form of the Eye Cancer Retinoblastoma

question 32

Multiple Choice

Matthew has the inherited form of the eye cancer retinoblastoma.His disease is caused by

• A) a germinal mutation in one RB allele, and no mutation in the other allele.
• B) a somatic mutation in each copy of the RB gene in the same cell.
• C) a germinal mutation in one RB allele, then a somatic mutation in the other allele.
• D) a somatic mutation in the one of the RB genes in the same area of the retina of one eye.
• E) activation of the X-linked oncogene RB.

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