The First Single-Gene Disorder for Which the Mechanism of Mutation

question 5

Multiple Choice

The first single-gene disorder for which the mechanism of mutation was understood was

• A) cystic fibrosis.
• B) Duchenne muscular dystrophy.
• C) hemophilia.
• D) sickle cell disease.
• E) diabetes mellitus.

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Definitions:

Cerebrum

The largest part of the brain, responsible for higher brain functions, including sensory perception, reasoning, emotions, and motor skills.

Limbic System

An intricate network of neural pathways and regions in the brain, located close to the cortex boundary, that plays a crucial role in managing instinctual behavior and emotional responses. It governs fundamental emotions such as fear, joy, and anger, along with primary drives like appetite, sexual desire, dominance, and parental instincts.

Hypothalamus

A small region of the brain that plays a crucial role in many essential functions, including releasing hormones, regulating body temperature, and maintaining daily physiological cycles.

Forebrain

The anterior part of the brain, including the cerebral hemispheres, thalamus, and hypothalamus, responsible for complex behaviors and mental processes.