Your Toxicology Testing Facility Tests Urine Samples

question 3

Multiple Choice

Your toxicology testing facility tests urine samples.New screening tests for methamphetamine and amphetamine have been added to the drug profiles.Occasionally a positive methamphetamine immunoassay screening test is followed by a negative amphetamine confirmatory test result.What might cause this discrepancy?

• A) Recent use of hydrocodone would give a negative amphetamine result,as it blocks the reaction on the screening test.
• B) If the specimen contained ephedrine or pseudoephedrine,it might test positively for methamphetamine but not amphetamine.
• C) False-negative results are common,especially when the immunoassay is performed without prior glucuronide hydrolysis.
• D) Other chemically related compounds such as pseudoephedrine have been shown to produce positive results in amphetamine immunoassays.

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