Explain Which Measures Led to the Development of Resistance to Amantadine

question 33

Essay

Explain which measures led to the development of resistance to amantadine and rimantadine in the H5N1 influenza virus and why this resistance is a problem.Are there any alternative drugs to combat H5N1 and,if so,could sufficient protection be provided if there was an influenza pandemic?

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Definitions:

Continental Hot Spot

A volcanic region thought to be fed by underlying mantle that is anomalously hot compared with the surrounding mantle, found in the interior of continental plates.

Yellowstone National Park

A national park primarily located in Wyoming, USA, known for its wildlife and its many geothermal features, especially Old Faithful geyser.

Afar Region

A geologically active area located in the Horn of Africa, known for its unique geological features including the Afar Triangle and part of the Great Rift Valley.

Crystalline Rocks

Rocks composed of crystals that are tightly interlocked, typically formed through the cooling and solidification of magma or by metamorphism.