You Have Been Asked to Direct a Pharmacogenetics Testing Laboratory

question 4

Multiple Choice

You have been asked to direct a pharmacogenetics testing laboratory in a hospital with many transplant patients who receive mercaptopurine derivatives to control transplant rejection.Which of the following enzyme phenotyping or genotyping services would be the highest priority to establish initially?

• A) N-acetyltransferase genotyping
• B) Thiopurine methyltransferase (TPMT)genotyping
• C) CYP1A1 genotyping
• D) CYP2D6 phenotyping

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