[Solved] Which of the following microbial forms have the highest resistance to physical and chemical controls? A)naked viruses B)protozoan cysts C)fungal spores D)bacterial endospores E)yeast Pubertal Changes: Physical and hormonal transformations occurring during puberty that lead to sexual maturity and the ability to reproduce. Deepening of the Voice: A change that typically occurs during puberty, involving the lowering of vocal pitch, especially noted in males. Four-Year Institution: An educational establishment that offers bachelor's degrees and typically requires four years of full-time study. Public University: An institution of higher education and research which is supported by public funds and usually affiliated with a national or state government.