Select the Statement That Best Explains the Mechanism of Action

question 6

Multiple Choice

Select the statement that best explains the mechanism of action of alendronate (Fosamax) ,pamidronate (Aredia) ,risedronate (Actonel) ,and zoledronate (Reclast) .

• A) The nonnitrogen bisphosphonates are attracted to bone calcium and have greater resorption inhibition potency. These drugs [alendronate (Fosamax), pamidronate (Aredia), risedronate (Actonel), and zoledronate (Reclast)] compete with osteoclast ATP, causing the cells to die; thus, bone resorption decreases.
• B) The nonnitrogen bisphosphonates [alendronate (Fosamax), pamidronate (Aredia), risedronate (Actonel), and zoledronate (Reclast)] compete with osteoclast ATP, causing the cells to die; thus, bone resorption decreases.
• C) The nitrogen bisphosphonates are more readily attracted to bone calcium and have greater resorption inhibition potency. These drugs [alendronate (Fosamax), pamidronate (Aredia), risedronate (Actonel), and zoledronate (Reclast)] prevent protein synthesis in the osteoclast cell membrane by interrupting the HMG-CoA reductase pathway.
• D) None of these are correct.

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Definitions:

Feelings of Persecution

A psychological condition where individuals feel they are being targeted for harm or harassment by others.

Antisocial Personality Disorder

A mental health disorder characterized by a long-term pattern of disregard for, or violation of, the rights of others.

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Lacking awareness or consideration for the feelings and circumstances of others; showing little empathy.

Society's Boundaries

The limits or borders defined by a society that delineate acceptable behaviors, practices, and norms within that society.