Select the Statement That Best Explains the Mechanism of Action

question 6

Multiple Choice

Select the statement that best explains the mechanism of action of alendronate (Fosamax) ,pamidronate (Aredia) ,risedronate (Actonel) ,and zoledronate (Reclast) .

• A) The nonnitrogen bisphosphonates are attracted to bone calcium and have greater resorption inhibition potency. These drugs [alendronate (Fosamax), pamidronate (Aredia), risedronate (Actonel), and zoledronate (Reclast)] compete with osteoclast ATP, causing the cells to die; thus, bone resorption decreases.
• B) The nonnitrogen bisphosphonates [alendronate (Fosamax), pamidronate (Aredia), risedronate (Actonel), and zoledronate (Reclast)] compete with osteoclast ATP, causing the cells to die; thus, bone resorption decreases.
• C) The nitrogen bisphosphonates are more readily attracted to bone calcium and have greater resorption inhibition potency. These drugs [alendronate (Fosamax), pamidronate (Aredia), risedronate (Actonel), and zoledronate (Reclast)] prevent protein synthesis in the osteoclast cell membrane by interrupting the HMG-CoA reductase pathway.
• D) None of these are correct.

Recognize the cultural impact on naming conventions and personal identity choices.

Understand how collectivist cultures prioritize family and community duties over individual choices.

Identify the geographical regions where collectivism and individualism are predominantly emphasized.

Recognize the cultural predisposition towards interpreting social behaviors and norms.

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Definitions:

Absolute Threshold

The minimum stimulus intensity required to detect a particular stimulus 50% of the time.

Adaptation Threshold

The limit to which an organism or a system can adapt to changes in conditions or stimuli.

Difference Threshold

The smallest amount of change in a stimulus that can be detected as different from the original stimulus.

Subliminal Threshold

The level below which a stimulus is not consciously detected but can still influence thoughts, feelings, or actions.