Select the Mechanism of Action of Trimethadione (Tridione) and the Oxazolidinedione

question 16

Multiple Choice

Select the mechanism of action of trimethadione (Tridione) and the oxazolidinedione class of drug agents.

• A) Trimethadione (Tridione) reduces the T-type calcium currents in the thalamus, which reduces the occurrence of seizures.
• B) Trimethadione (Tridione) attaches to plasma protein, causing a reduction in the occurrence of seizures.
• C) Trimethadione (Tridione) increases the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA). In the brain, this suppresses the excitability of epileptogenic neurons and makes them less likely to discharge and initiate a seizure.
• D) None of these are correct.

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