Select the Statement That Best Explains the Mechanism of Action

question 28

Multiple Choice

Select the statement that best explains the mechanism of action of the laxative products Ceo-Two and lubiprostone (Amitiza) .

• A) Lubiprostone (Amitiza) releases carbon dioxide gas, which pushes on the wall of the rectum, inducing muscle contractions and stool movement, whereas Ceo-Two opens the chloride channels so that chloride followed by water enters the channels in an attempt to maintain isotonic balance, accelerating transit time and softening the stool.
• B) Ceo-Two releases carbon dioxide gas, which pushes on the wall of the rectum, inducing muscle contraction and stool movement, whereas lubiprostone (Amitiza) opens the chloride channels so that chloride followed by water enters the channels in an attempt to maintain isotonic balance, accelerating transit time and softening the stool.
• C) Both lubiprostone (Amitiza) and Ceo-Two open the chloride channels so that chloride followed by water enters the channels in an attempt to maintain isotonic balance, accelerating transit time and softening the stool.
• D) Ceo-Two releases carbon dioxide gas, which pushes on the wall of the rectum, inducing muscle contractions and stool movement, whereas lubiprostone (Amitiza) stimulates mu receptors in the myenteric plexus to decrease peristalsis, constrict sphincters, and directly affect the circular smooth muscle of the bowel, accelerating the gastrointestinal transit time.

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