Select the Mechanism of Action of Topiramate (Topamax)

question 26

Multiple Choice

Select the mechanism of action of topiramate (Topamax) .

• A) Topiramate interferes with the action of Na+ ions and the generation of high-frequency action potentials. The drug may also increase the inhibitory actions of gamma-aminobutyric acid.
• B) Topiramate shortens the inactivation period of sodium ion (Na+) channels in the nerve membrane, leading to a reduction in the generation of high-frequency repetitive firing of action potentials from neurons involved in initiating seizures.
• C) Topiramate reduces the T-type calcium currents in the thalamus, which reduces the occurrence of seizures.
• D) Topiramate prolongs the inactivation period of potassium (K+) channels in the nerve membrane, leading to a reduction in the generation of high-frequency repetitive firing of action potentials from neurons involved in initiating seizures.

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Definitions:

Activity-Based Costing

A costing methodology that identifies activities in an organization and assigns the cost of each activity to all products and services according to the actual consumption by each.

Overhead Cost

Expenses not directly tied to production but necessary for running the business, such as rent, utilities, and salaries for administrative staff.

Activity-Based Costing

An accounting method that apportions overhead and incidental costs to the respective products and services based on the specific activities involved.

Worker Recreational Facilities

Facilities provided by employers for employees' relaxation and leisure, aiming to improve morale and productivity.