Why Does a Replication Fork Have a Leading and Lagging

question 17

Multiple Choice

Why does a replication fork have a leading and lagging strand?

• A) because DNA synthesis always goes from 5' to 3'
• B) because DNA polymerase only attaches nucleotides to the 3' end of strands
• C) because DNA synthesis can grow off of either the 3' or 5' end
• D) because DNA synthesis always goes from 3' to 5'
• E) Both answers, with DNA synthesis proceeding from 5' to 3', and DNA polymerase only acting on the 3' end, are correct.

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