Why Do Metabolic Pathways Require Tens to Hundreds of Different

question 1

Multiple Choice

Why do metabolic pathways require tens to hundreds of different enzymes?

• A) The enzymes are used up after one reaction and the molecules have to undergo multiple rearrangements.
• B) The enzyme is deformed by the interaction with the substrate and needs a period of time to return to its original reactive form, so many enzymes are needed to keep the pathway going.
• C) Each enzyme has a specific substrate and produces a specific product.
• D) Multiple enzymes are not required for the pathway, but having them speed up the production of the final product.
• E) The enzymes are attached to a membrane and cannot move to the location of the new intermediate, so having a long line of enzymes to carry out the reaction allows the reaction to occur faster.

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Definitions:

Spearman Rank

It's a method for assessing rank correlation without assuming any parameter, focusing on how a monotonic function might accurately describe the connection between two variables.

Ordinal Variables

Variables that represent categories with a meaningful order but without a fixed interval between categories, such as rankings or levels of satisfaction.

Pearson's Coefficient

A measure of the linear correlation between two variables, ranging from -1 to 1, where 1 means a perfect positive linear relationship and -1 a perfect negative linear relationship.

Spearman Rank

A rank correlation metric that is non-parametric and evaluates the extent to which two variables' association can be explained through a monotonic function.