How Does Phenyl Isothiocyanate, Ph−N=C=S, React with a Peptide in the Edman

question 8

Multiple Choice

How does phenyl isothiocyanate, Ph−N=C=S, react with a peptide in the Edman degradation?

• A) the sp carbon acts as an electrophile in a reaction with an amino group of the peptide
• B) the sulfur acts as a nucleophile and adds to the carbon of the peptide bond
• C) the nitrogen acts as a nucleophile and adds to the carbon of the peptide bond
• D) the sp carbon acts as an electrophile in a reaction with a carboxylate of the peptide

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Definitions:

Fibrous Capsule

A dense connective tissue layer that encloses certain organs and joints, providing support and protection.

Synovial Joint

A freely movable joint characterized by a cavity filled with synovial fluid, which lubricates and nourishes the cartilage-covered articulating surfaces.

Articular Cartilage

A smooth, white tissue that covers the ends of bones at joints, enabling easy movement and reducing friction.

Synovial Fluid

A viscous, non-Newtonian fluid found in the cavities of synovial joints, reducing friction between articular cartilages during movement.