In Sickle Cell Hemoglobin, a Glu Is Mutated to a _______

question 21

Multiple Choice

In sickle cell hemoglobin, a Glu is mutated to a _______. This causes the formation of _______ between hemoglobin molecules, ultimately forming large aggregates.

• A)Arg; salt bridges
• B)Cys; disulfide bonds
• C)Val; hydrophobic interactions
• D)Pro; disrupted \(\alpha\)-helix, resulting in several H-bonds and salt bridges
• E)none of the above

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