The Transcription Factor PGC-1 $\alpha$ Is Controlled by Two Forms of Covalent Modification

question 2

Multiple Choice

The transcription factor PGC-1 $\alpha$ is controlled by two forms of covalent modification. Which of the following correctly identifies a mechanism of control?

• A)phosphorylation by AMPK inhibits PGC-1\(\alpha\)
• B)dephosphorylation by AMPK activates PGC-1\(\alpha\)
• C)acetylation by SIRT1 activates PGC-1\(\alpha\)
• D)deacetylation by SIRT1 activates PGC-1\(\alpha\)
• E)dephosphorylation by AMPK and deacetylation by SIRT1 activates PGC-1\(\alpha\)

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Definitions:

Elastic Supply

A situation where the quantity supplied changes significantly in response to changes in price.

Elastic Demand

A situation where the demand for a product or service significantly changes in response to a change in price.

Inelastic Supply

A situation where the quantity supplied of a good is not significantly affected by a change in price.

Elastic Demand

A market condition where the demand for a product is sensitive to price changes, meaning that a small change in price results in a large change in the quantity demanded.