Which of the Following Substituted Cyclohexanes Has the Most Negative $\Delta$

question 11

Multiple Choice

Which of the following substituted cyclohexanes has the most negative value of $\Delta$ G ^$\circ$ for ring flipping from the conformation in which the substituent is axial to the one where it is equatorial?

• A)fluorocyclohexane
• B)methylcyclohexane
• C)ethylcyclohexane
• D)tert-butylcyclohexane