Which of the Following Substituted Cyclohexanes Has the Most Negative $\Delta$

question 34

Multiple Choice

Which of the following substituted cyclohexanes has the most negative value of $\Delta$ G ^$\circ$ for ring flipping from the conformation in which the substituent is axial to the one where it is equatorial?

• A)methylcyclohexane
• B)chlorocyclohexane
• C)isopropylcyclohexane
• D)ethynylcyclohexane

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