Outline how one might achieve the following transformation, showing reagents and the isolated intermediates in the synthetic scheme. 
Definitions:
Smooth ER
The smooth endoplasmic reticulum, a membrane-bound organelle involved in lipid synthesis, metabolism, and detoxification processes in cells.
Nucleolus
A small, dense structure within the nucleus of a cell, primarily involved in the production and assembly of ribosomes.
Ribosome
Small, spherical, cytoplasmic organelle where protein synthesis occurs.
Chromosome
A structure made of DNA and proteins that contains the genetic information of a cell.
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