Give the First Step of the Mechanism for Aldolase

question 79

Multiple Choice

Give the first step of the mechanism for aldolase.

• A)Fructose-1,6,-diphosphate forms an imine with a lysine residue at the active site of the enzyme.
• B)A tyrosine residue functions as a base catalyst to cleave the bond between C-3 and C-4.
• C)The enamine intermediate rearranges to an imine.
• D)Hydrolysis of the imine releases dihydroxyacetone phosphate.
• E)A molecule of glyceraldehyde-3-phosphate is expelled.

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