Which of the Following Best Describes a Proper a Dose-Response

question 41

Multiple Choice

Which of the following best describes a proper a dose-response assessment of a metered-dose inhaler (MDI) bronchodilator?

• A)Give 4 puffs one after the other, wait 1 minute, repeat up to 16 puffs. The best dose is the highest dose given without side effects.
• B)Give 4 puffs spaced 1 to 2 minutes apart; repeat up to 12 puffs with continued improvement. The best dose provides maximum subjective relief and the highest peak expiratory flow rate (PEFR) without side effects.
• C)Give 12 puffs 1 minute apart; repeat every 20 minutes until maximum relief of symptoms is achieved without side effects.
• D)Give 2 puffs 1 to 2 minutes apart; repeat up to 6 puffs with continued improvement. The best dose provides maximum subjective relief and the highest PEFR without side effects.

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