I Propose to Design a New Drug Which Will Act

question 32

Multiple Choice

I propose to design a new drug which will act as an inhibitor for an enzyme.If I have used all current information about the mechanism of this enzyme to design this inhibitor and I carefully engineer it with similar chemical properties of the transition state,what type of inhibitor am I attempting to engineer and how will I know if I have succeeded?

• A)A competitive inhibitor,collect kinetic data both in the presence and absence of inhibitor and watch for a change in V_max.
• B)A competitive inhibitor,collect kinetic data both in the presence and absence of inhibitor and watch for a change in K_M.
• C)A uncompetitive inhibitor,collect kinetic data both in the presence and absence of inhibitor and watch for a change in K_M.
• D)A uncompetitive inhibitor,collect kinetic data both in the presence and absence of inhibitor and watch for a change in V_max.
• E)None of the above.

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Definitions:

Hearing Loss

A decrease in the ability to perceive sounds compared to normal hearing levels.

Pretending

The act of making believe or acting in a way that is not true or real, often as a form of play or deception.

Hearing Loss

A partial or total inability to hear sounds in one or both ears, which can be temporary or permanent and vary in severity.

Speaking Loudly

The act of increasing vocal volume beyond regular speaking levels, often to ensure audibility in noisy environments or to display emphasis.