Autoinhibition in the SH2 and SH3 Domains

question 27

Multiple Choice

Autoinhibition in the SH2 and SH3 domains

• A)occurs when a SH2 phospho-Tyr forms a salt bridge with an Arg on SH3.
• B)occurs when a SH2 phospho-Tyr binds a Pro segment on the SH3 domain,therefore blocking the active site and burying the required Tyr.
• C)occurs when a salt bride forms between the active site phosphor-Tyr on SH3 and the Glu on the activation loop.
• D)occurs when the salt bridge between Glu and Arg is broken.
• E)None of the above is correct.

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Definitions:

Mechanical Isolation

A form of reproductive barrier where differences in the size and shape of reproductive organs prevent mating between species.

Sympatric Speciation

The evolution of a new species within the same geographic region as the parental species. Compare with allopatric speciation.

Experimental Hybrids

Organisms created through the crossbreeding of two different species or genetically distinct individuals in a controlled environment, often for research purposes.

Laboratory Conditions

Controlled environmental settings in which scientific or technological research, experiments, and measurement are performed.