A Prokaryotic Replisome Typically Contains Two Molecules of DNA Pol

question 14

Multiple Choice

A prokaryotic replisome typically contains two molecules of DNA pol III,but only one molecule of DNA pol I.Why?

• A)The DNA pol I works on the leading strand,while DNA pol IIIs work on the Okazaki fragments.since there are several of those,it takes more proteins to keep up.
• B)DNA pol I has a built-in proofreading exonuclease;DNA pol III does not.The second DNA pol III is needed to follow the first to accomplish the necessary proofreading.
• C)The DNA pol IIIs work at one replication fork,while the DNA pol I works at the other.This way they don't meet exactly at the other side of the chromosome.
• D)The DNA pol IIIs do most of the work.DNA pol I only has to work on the telomers.
• E)DNA pol I replaces the RNA primers with DNA,which really only needs to be done repetitively on one strand,while both strands are worked on by the DNA pol IIIs.

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