Why Do Changes in PH Interfere with the Function of Proteins

question 5

Multiple Choice

Why do changes in pH interfere with the function of proteins? For your answer, consider the acid/base character of many amino acid side chains.

• A)At high pH the acidic side chains of amino acids such as glutamic acid and tyrosine will become negatively charged as they lose a hydrogen ion.
• B)At low pH the alkaline side chains of amino acids such as lysine and histidine will become positively charged as they gain a hydrogen ion.
• C)A change in pH can result in a change in the type of molecular attractions that occur among amino acids within a polypeptide.
• D)all of the above

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