Bruce Ames Constructed a Mutagenicity Test Which Initially Missed Carcinogens

question 27

Multiple Choice

Bruce Ames constructed a mutagenicity test which initially missed carcinogens which were noncarcinogenic to the tester strains.Why?

• A) Tester strains were more resistant to the mutagenic effects of the carcinogen than eukaryotes
• B) Not all carcinogens are mutagens
• C) Potential carcinogens needed to be modified in eukaryotes before they were mutagenic
• D) Histidine biosynthesis was inhibited by the presence of the carcinogens.
• E) All of these

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