When Testing for the Presence of the Sickle Cell Anemia

question 18

Multiple Choice

When testing for the presence of the sickle cell anemia Hbb allele,a Southern blot exhibits two small bands for the Hbb? allele and one band for the Hbb allele.What do these results mean?

• A) The subject is homozygous for the sickle cell allele
• B) The subject is heterozygous
• C) The subject is homozygous for the normal allele
• D) The results are inconclusive and the test will need to be run again
• E) Southern blots cannot test for the presence of the sickle cell allele

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