Mutations in HPC1

question 47

Multiple Choice

Mutations in HPC1

• A) cause glioblastomas in the brain.
• B) lead to prostate cancer when mutations in TP53, RB, and NF2 also occur.
• C) is the gene for the inherited form of prostate cancer.
• D) require mutations in several other tumor suppressor genes to cause polyposis carcinomas.
• E) None of these

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Definitions:

Extremities

The furthest or most remote points, parts, or boundaries of an area, structure, or part.

Profile Tolerance

A geometric dimensioning and tolerancing method that specifies the allowable variation of a surface's profile.

True Profile

The accurate outline or contour of an object's surface as specified in design documentation.

Circular Runout

Circular runout is a tolerance specified on cylindrical parts to control the amount of variation or wobbles as the part rotates around a datum axis.