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The Following Pedigree Concerns the Autosomal Recessive Disease Phenylketonuria (PKU)

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The following pedigree concerns the autosomal recessive disease phenylketonuria (PKU) .The couple marked A and B are contemplating having a baby but are concerned about the baby having PKU.What is the probability of the first child having PKU? Unless you have evidence to the contrary,assume that a person marrying into the pedigree (i.e.,not a descendant of the two parents at the top of the pedigree) is not a carrier.The filled-in individuals have PKU. The following pedigree concerns the autosomal recessive disease phenylketonuria (PKU) .The couple marked A and B are contemplating having a baby but are concerned about the baby having PKU.What is the probability of the first child having PKU? Unless you have evidence to the contrary,assume that a person marrying into the pedigree (i.e.,not a descendant of the two parents at the top of the pedigree) is not a carrier.The filled-in individuals have PKU.   A) 0 B) 1/12 C) 1/4 D) 3/4 E) 9/64

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Definitions:

Sphygmomanometers

Instruments used to measure blood pressure, typically consisting of a cuff, gauge, and a mechanism for inflation.

Hyperpnea

An increased depth and rate of breathing, often in response to exercise or the body's need for more oxygen.

Aneroid Sphygmomanometers

A type of blood pressure monitor that uses a mechanical gauge without the need for mercury to measure blood pressure.

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