The Following Pedigree Concerns the Autosomal Recessive Disease Phenylketonuria (PKU)

question 12

Multiple Choice

The following pedigree concerns the autosomal recessive disease phenylketonuria (PKU) .The couple marked A and B are contemplating having a baby but are concerned about the baby having PKU.What is the probability of the first child having PKU? Unless you have evidence to the contrary,assume that a person marrying into the pedigree (i.e.,not a descendant of the two parents at the top of the pedigree) is not a carrier.The filled-in individuals have PKU.

• A)0
• B)1/12
• C)1/4
• D)3/4
• E)9/64

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Definitions:

Control Charts

Control charts are tools used in quality control to monitor process variations and identify whether a process is in a state of statistical control.

Process Variables

Variables that are measured, monitored, or controlled during a process to ensure optimal quality or performance.

Sample Means

The average value of a set of sample data, used to estimate the population mean.

Standard Deviation

An index of how much individual observations of a dataset vary from the dataset's mean.