Vanessa Has Obtained Two True-Breeding Strains of Mice,each Homozygous for an Independently

question 12

Essay

Vanessa has obtained two true-breeding strains of mice,each homozygous for an independently discovered recessive mutation that prevents the formation of hair on the body.The discoverer of one of the mutant strains calls his mutation naked,and the other researcher calls her strain hairless.To determine whether the two mutations are simply alleles for the same gene,Vanessa crosses naked and hairless mice with each other.All the offspring are phenotypically wild type.After intercrossing these F₁ mice,however,Vanessa observes 115 wild-type mice and 85 mutant mice in the F₂.
a)What is the most likely explanation for the segregation of wild-type mice and mutant mice in the F₂? Are the naked and hairless mutations alleles for the same gene?
b)Using symbols of your own choosing,indicate the genotypes of the parents,the F₁,and each of the phenotypic classes of the F₂ progeny.Describe any gene interactions in this set of crosses.

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