Which of the Following Is the Most Sensible Order of Techniques

question 22

Multiple Choice

Which of the following is the most sensible order of techniques for mapping a chromosome and then locating a specific disease gene?

• A)contig alignment;restriction mapping;RFLP linkage analysis;chromosomal walking
• B)chromosomal walking;contig alignment;restriction mapping;RFLP linkage analysis
• C)restriction mapping;chromosomal walking;contig alignment;RFLP linkage analysis
• D)chromosomal walking;restriction mapping;RFLP linkage analysis;contig alignment
• E)restriction mapping;contig alignment;RFLP linkage analysis;chromosomal walking

---

Definitions:

Unbiased Estimator

A statistical estimator that is expected to equal the true parameter of the population being studied.

Consistent Estimator

A statistical property where an estimator of a parameter tends to converge to the true parameter value as the sample size increases.

Variance

A measure of variability that quantifies the spread of a set of data points around the mean.

Confidence Level

The probability or degree of certainty that a confidence interval would contain the true population parameter if the same procedure were repeated multiple times.