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Some Indel Mutations Can Be Created Spontaneously as a Result

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Essay

Some indel mutations can be created spontaneously as a result of errors during DNA replication.
a)Use diagrams to show how 1)insertions and 2)deletions are spontaneously created as a result of the replication of tandem repeats.
b)Give the term used to describe this process.
c)Name two human diseases that arise as a consequence of expanded trinucleotide repeats in DNA.
d)Describe two ways in which expanded trinucleotide repeats can cause disease.

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Definitions:

Maturity Value

The amount payable to an investor at the end of a fixed term investment, including principal and interest.

Monthly Compounded

A reiteration indicating that the interest accrues on a monthly basis, thereby increasing the investment or loan amount through compounding.

Promissory Note

A written and signed promise to pay a specified sum of money to a particular person or bearer on a specified date.

Compounded Semi-Annually

The process of calculating interest on both the initial principal and the accumulated interest over half-year periods.

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