In Drosophila,the Phenotype Bar-Eye Is Due to a Tandem Duplication

question 27

Essay

In Drosophila,the phenotype bar-eye is due to a tandem duplication of several bands on the X chromosome.Occasionally (1 out of 1600),all true-breeding stocks of bar-eyed flies yield an even more extreme phenotype called ultrabar,which is in fact due to a triplication of this chromosomal segment.The hypothesis used to explain ultrabar's origin is that a slight mispairing of chromosomes can occur whenever there is a duplication.If crossing-over occurs (in females),then recombinants would form as follows:
What other evidence,not involving cytological observation,would you seek to substantiate this hypothesis? Be as exact as you can.There are at least two possible answers.

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