In 1947,Sidney Farber Injected a Two-Year-Old Boy Who Had Leukemia

question 139

Essay

In 1947,Sidney Farber injected a two-year-old boy who had leukemia with various versions of an experimental drug that led to remission.By the next year he had treated 16 patients and had enough data for a publication.Parents were sometimes told about the drug trial,but often it was after the fact.Children were almost never informed or consulted.Authorities at Children's Hospital in Boston were infuriated at these clinical trials; they figured that because these children were on their deathbeds anyways,it would be better to "let them die in peace." Can clinical trials such as these be carried out with children today? Why or why not?

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