Which of the Following Interactions Causes a Change from the R

question 18

Multiple Choice

Which of the following interactions causes a change from the R state (oxy form) to the T state (deoxy form) of hemoglobin?

• A)interactions between heme groups
• B)protonation of the R-group of His146 on the \(\beta\) subunit to allow formation of a salt bridge with Lys40 on the \(\alpha\) subunit
• C)salt bridge formed by \(\alpha\) 1-Arg141 to the carboxylate of \(\alpha\) 2Asp126
• D)protonation of the \(\alpha\) 1 subunit terminal carboxyl group disrupts a salt bridge with \(\alpha\) 2Lys 127
• E)none of the above

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