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Enolates Are Frequently Formed by Treating an Aldehyde or Ketone

question 76

Essay

Enolates are frequently formed by treating an aldehyde or ketone with LDA.However,the LDA must first be generated by reacting diisopropylamine with butyllithium.Why don't chemists just use butyllithium itself to deprotonate the aldehyde or ketone and form the enolate?


Definitions:

Nuclei

The plural of nucleus, referring to the membrane-bound organelles that contain the genetic material in eukaryotic cells.

Mammalian

Pertaining to mammals, a class of warm-blooded animals characterized by the presence of mammary glands, which females use to feed their young.

Vertebrates

Animals with a backbone or spinal column, which includes fish, amphibians, reptiles, birds, and mammals.

Hemoglobin

A protein in red blood cells that carries oxygen from the lungs to the tissues of the body and returns carbon dioxide from the tissues to the lungs.

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