Give the First Step of the Mechanism for Aldolase

question 79

Multiple Choice

Give the first step of the mechanism for aldolase.

• A)Fructose-1,6,-diphosphate forms an imine with a lysine residue at the active site of the enzyme.
• B)A tyrosine residue functions as a base catalyst to cleave the bond between C-3 and C-4.
• C)The enamine intermediate rearranges to an imine.
• D)Hydrolysis of the imine releases dihydroxyacetone phosphate.
• E)A molecule of glyceraldehyde-3-phosphate is expelled.

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Definitions:

Urea

Urea is a nitrogenous compound produced in the liver as a waste product of protein metabolism and excreted in urine.

Beta Oxidation

A metabolic process in which fatty acid molecules are broken down in the mitochondria to generate acetyl-CoA, which enters the citric acid cycle to produce energy.

Fatty Acids

Long hydrocarbon chains that are a vital component of lipids and play an essential role in energy storage and cell structure.

Catabolized

The process by which substances are broken down into smaller molecules to release energy.