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Phosphoglucomutase Catalyses the Reaction in Which a Phosphate Group Is \leftrightarrows

question 32

Essay

Phosphoglucomutase catalyses the reaction in which a phosphate group is transferred from the 1 carbon of glucose to the 6 carbon of glucose (G1P \leftrightarrows G6P).A student at SDSU incubates a 0.2 M solution of glucose-1-phosphate overnight with a small amount of the enzyme.At equilibrium the concentration of glucose 1-phosphate is 9.0 × 103 M and the concentration of glucose 6-phosphate is 19.1 × 102 M.
Calculate the equilibrium constant (Keq)and the standard state free energy (∆G°')for this reaction at 25°C.


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