Examine the Three Sequences Below for Collagen-Like Proteins and Their

question 56

Multiple Choice

Examine the three sequences below for collagen-like proteins and their melting temperatures (Tm) .(Note: Flp = fluoroproline;Hyp = hydroxyproline) Based on this data,what is the most important feature in determining the strength of the collagen protein?
1) …-Pro-Hyp-Gly-Pro-Hyp-Gly-Pro-Hyp-Gly-… Tm=60^oC
2) …-Pro-Flp-Gly-Pro-Flp-Gly-Pro-Flp-Gly-… Tm=78^oC
3) …-Gly-Pro-Thr-Gly-Pro-Thr-Gly-Pro-Thr-… Tm=30^oC

• A)hydrogen bonding
• B)inductive effect
• C)electrostatic effect
• D)electrostatic and Inductive effect are equal
• E)hydrogen bonding and inductive effect are equal

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