Why Is the Decreased Affinity of Fetal Hemoglobin for BPG

question 45

Multiple Choice

Why is the decreased affinity of fetal hemoglobin for BPG advantageous?

• A)With fewer BPG molecules bound there are more heme residues available for O₂ binding.
• B)Decreased BPG binding biases the fetal hemoglobin toward the R state.
• C)More free BPG is available to bind to adult hemoglobin,resulting in a shift to the R state.
• D)BPG is available to bind to fetal myoglobin,helping to release O₂ in fetal muscle tissue.
• E)none of the above

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