Which Statement About Antigen-Binding Sites in Antibodies Is False

question 56

Multiple Choice

Which statement about antigen-binding sites in antibodies is false?

• A)An antigen-binding site on an IgG is formed by the amino-terminal ~110 amino acids of a light chain and the amino terminal ~110 amino acids of a heavy chain.
• B)An antigen-binding site on an IgG is formed by the variable region of a light chain and the variable region of a heavy chain.
• C)The antigen-binding site is composed of two Ig folds.
• D)Antigen-binding specificity is determined by the sequences of the hypervariable sequences in both the light chain and the heavy chain.
• E)Antigen binding specificity is determined exclusively by the sequences in the carboxy-terminal ~110 amino acids in the light chain and the heavy chain.

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