An Extremely Efficient Enzyme Called "Efficase" Catalyzes the Conversion of "A

question 47

Multiple Choice

An extremely efficient enzyme called "efficase" catalyzes the conversion of "A" to "B." A researcher decides to mutate the enzyme in order to try to improve its performance.Following active site mutations,a significant reduction in the value of K_M and V_max was observed.Which of the following may have occurred?

• A)The affinity of the enzyme for the substrate was increased to a point which did not favor propagation (continuation)of the reaction.
• B)The decrease in V_max was not related to the decrease in K_M.
• C)If the reaction was first-order,the change in K_M cannot have affected V_max.
• D)The stability of E+S (E+A as written above)was increased,thereby increasing the K_M.
• E)The reverse reaction (breakdown of EA to E+A)was favored,slowing the V_max.

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Definitions:

Communication Feasibility

Refers to the practicality and possibility of effectively transmitting information between parties.

Social Order

The system of structured relationships, norms, and practices that maintain a cooperative and cohesive society.

Stress Reliever

An activity, practice, or behavior that reduces psychological tension or manages the effects of stress.

Economic Inequality

The unequal distribution of wealth, income, or resources among individuals, communities, or countries, often leading to social and economic disparities.